Hmm. Hits for me include the new framework.
A miss in my opinion are underuse by the OS of that framework. The Aero style, for example, is bitmap based, and it really should be XAML vectors (again my ignorant opinion).
The biggest miss for me was that MSIE crashes if I don't run it as an administrator - a particular pain in the ass with Vista. And, since many of the default desktop and start menu icons open IE, I was experiencing a lot of freezes. People said update Java runtimes, but that didn't work. So, a big miss for me is Vista plain doesn't work.
But the thing that prevented me from trying to chase down this bug further is the incessant "security" confirmations. As if malware changing the screen resolution or font size is a real problem. Vista discourages customization and tweaking with all these "Are You Sures", which don't just pop up. They pause responsiveness, do some funky resolution thing, make you think its busted, then appear in a random location.
I personally simply won't be able to use an operating system that interrupts workflow to the extent the Beta 2 does in the name of security.
Another miss is general lack of feedback. Frequently one can click a button for example, and the cursor doesn't change, the button doesn't change, nothing to tell you if things are working.