I didn't explain myself clearly. Need to remove it from every users profile on a Windows 2012 Remote Desktop Server Farm. Don't want to go into each user profile and do one at a time. I'm looking for either a group policy or registry setting to do the trick.

You should be able to stop the shortcut being created on first login in one of two ways.

1) Set on a per account basis the following registry key :

Location : HKEY_CURRENT_USER\Software\Stardock\Start8\Start8.ini\Start8

Key : DoNotCreateWin8Link

Value : 1 (store as a REG_SZ)

or

2) Set on a per machine basis using the following registry key :

Location : HKEY_LOCAL_MACHINE\Software\Stardock\Start8\Start8.ini\Start8

Key : DoNotCreateWin8Link

Value : 1  (store as a REG_SZ)

Note that once the shortcut has been created there is no Start8 setting to remove it, though deleting the windows 8 menu.lnk from the usual pinned shortcuts folder would also do the trick.

As you are installing it on remote desktop servers, obviously please do make sure you have sufficient licenses.