Often times if I reload (usually from auto) I lose quest info. Such as a village being spawned that I am suppose to visit, but it not being there after I reload, although the quest icon is still there. Breaks the quest.
I also often find my units on top of quest / goodie huts when I load from auto - i guess it saves just before they move sometimes. I have to move them away and back onto the goodie hut / quest marker to trigger it.