I have been happily using Multipilicty on 3 machines (XP home, XP home, 2000) for a few months. However, I've encountered an issue (or more of an annoyance) since replacing one machine with Vista Home Premium 64 bit.
My setup is as follows:
Primary (middle): Vista Home Premium 64 bit
Secondary (left): Windows 2000
Secondary (right): XP Home
If I run Vista Home Premium as a standard user, there are no problems. However, as soon as I right click on a shortcut and select "run as administrator" (which I have to do for certain problems), then try to move my mouse to one of the secondaries, the cursor gets stuck on the edge of the screen, and I have to ALT TAB to regain the mouse for a few moments, the cursor then flickers while moving it and occasionally disappears.
As soon as I exit the program(s) that are running as adminstrator, normal service resumes and everything is peachy again.
Yes, I know I could just log in with the administrator account on Vista. But I figured I would point out this bug while running as a standard user anyway.