Thank you both for commenting.
Dr. Guy, you are correct in that the persecutions started in January of 1933. "After January 1933, the Jews became the "Untermenschen" - the sub-humans. Nazi thugs stopped Germans from shopping in Jewish shops. By 1934, all Jewish shops were marked with the yellow Star of David or had the word "Juden" written on the window. SA men stood outside the shops to deter anyone form entering."
In 1938, the Krystalnacht or Night of Broken Glass occured. But as to the word "Holocaust" as a description "According to the Oxford English Dictionary, the word was first used to describe Hitler's treatment of the Jews from as early as 1942, though it did not become a standard reference until the 1950s." After Wannsee, attacks reached a new level. Individual attacks, mass deporations, even murders of groups, were no longer enough for the Nazis. They would now begin the true genocide.
"In the spring of 1942, the Aktion Reinhard camps began operating. Carbon monoxide was used in the gas chambers at Belzec, Sobibór, and Treblinka, whereas Zyklon B was employed at Majdanek and Auschwitz.
The disposal of large numbers of bodies presented a logistical problem as well. Incineration was at first considered infeasible until it was discovered that furnaces could be kept at a high enough temperature to be sustained by the body fat of the bodies alone. With this technicality resolved, the Nazis implemented their plan of mass murder on its full scale."
Quotes from History Learning site and Wikipedia respectively.