I have two Asus Extreme N7800GTX in SLI mode that normally run between 32C-55C at max load. I've never seen either of them go over 55C even from the most graphically advanced games on the market.
So I load up Galciv 2 and moments later I notice there's a heat sensor warning going off on my case. I opened up the Nvidia display panel to see that both cards were at 70C and rising fast!
I think the game scales to your graphics power by a bit too much or something. Both these cards are being cooled by the stock heatsinks/fans plus two 120mm fans drawing heat away from them in a grated Lian-li case.
I bet a lot of CTD's and graphical artifacts that people are experiencing is from their video cards reaching abnormal temps.
And let me stress this again, it is only with Galciv 2 that I have encountered this.